一、学校简介

不列颠哥伦比亚大学（University of British Columbia，又译“英属哥伦比亚大学”等），简称UBC，位于加拿大温哥华市，始建于1908年，是一所公立大学。该校前身为麦吉尔大学不列颠哥伦比亚分校（McGill University College of British Columbia），于1915年获批独立。温哥华校区，位于加拿大第三大城市温哥华的市郊，距离温哥华只有30分钟的车程，校区占地达400公顷。这里有怡人的气候，绵延的海岸线，美丽的海洋与沙滩，是游览观光者必到之处。此外，温哥华校区还有该市最吸引人的许多学术及休闲娱乐设施，包括人类学博物馆、表演艺术中心、著名的UBC植物园及植物研究中心等。温哥华校区是UBC最大的校区，学生人数超过45,000名。不列颠哥伦比亚大学2024QS排名34。

二、实验室介绍

温哥华前列腺中心（VPC）为切尔卡索夫实验室的博士后研究员提供了一个难得的机会加入我们的研究团队。

该职位位于医疗机构内。因此，该职位需要根据省级卫生授权的要求，成功验证在开始日期之前提供的针对 Covid-19 的完全疫苗接种。

温哥华前列腺中心
VPC在基础、临床和转化癌症研究方面拥有大量多学科研究项目。它是国家卓越中心和指定的商业化和研究卓越中心。它隶属于不列颠哥伦比亚大学和温哥华沿海卫生局。

切尔卡索夫实验室 

阿尔乔姆·切尔卡索夫博士是不列颠哥伦比亚大学医学院泌尿外科科学系的教授，也是温哥华前列腺中心的高级科学家。他的研究兴趣包括计算机辅助药物发现（CADD）、结构活性建模、药物再分析、新的癌症疗法发现以及新型CADD工具和应用的开发。

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Research Fellow, Cherkasov Lab to join our research team.

This position is located within a health-care facility. Therefore, this position requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The Vancouver Prostate Centre
The VPC has a large number of multi-disciplinary research programs in basic, clinic, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority. 

Cherkasov Lab
Dr. Artem Cherkasov is a Professor in the Department of Urologic Sciences, Faculty of Medicine at the University of British Columbia, and Senior Scientist at the Vancouver Prostate Centre. His research interests include computer-aided drug discovery (CADD), structure-activity modeling, drug reprofiling, new cancer therapeutics discovery and development of novel CADD tools and applications.

三、资格和要求

Artem Cherkasov 教授正在寻找一位才华横溢的博士后研究员，该研究员在计算机辅助药物设计方面具有丰富的研究背景和经验。博士后研究员将致力于令人兴奋的药物发现项目，提供尖端的深度学习对接策略，以支持基于结构和配体的虚拟筛选和先导化合物优化。

◆较强的解决问题的能力和高效的沟通能力。

◆强大的 GPU 深度学习编程经验。

◆统计数据分析和数据库管理技能。

◆强大的 python、bash、Perl、awk 和 SVL 编程技能。

◆GitHub 上提供强大的开源软件组合。

◆在计算化学、生物化学、有机化学、药物化学和药代动力学方面具有扎实的背景。

◆在基于结构和配体的药物设计和化合物库设计方面的实践经验。

◆熟悉最先进的建模和化学信息学工具，如MOE、Schrodinger、OpenEye和ICM程序套件。

职责：

◆阅读已发表的论文并相应地调整程序。

◆与合作者联络，并在国际会议上展示研究成果。

◆为高影响力期刊准备稿件。

◆协助将研究提案提交给资助机构。

Professor Artem Cherkasov is looking for a talented Postdoctoral Fellow with a demonstrated research background and experience in computer-aided drug design. The Postdoctoral Fellow will work on exciting drug discovery programs providing cutting-edge Deep-learning docking strategy to support structure-based and ligand-based virtual screening and lead optimization.

◆ Strong problem solving and efficient communication skills.

◆ Strong Deep-learning programming experience with GPUs.

◆ Statistical data analysis and database management skills.

◆ Strong python, bash, Perl, awk, and SVL programming skills.

◆ Strong portfolio of open-source software available on GitHub.

◆Solid background in computational chemistry, biological chemistry, organic chemistry,medicinal chemistry and pharmacokinetics.

◆Hands-on experience in structure-based and ligand-based drug design and compoundlibrary design.

◆Familiarity with state-of-the-art modeling and cheminformatics tools such as MOE,Schrodinger, OpenEye and ICM suite of programs.

Duties

◆ Reading published papers and adapting procedures accordingly.

◆ Liaising with collaborators and present research findings in international conferences.

◆ Preparing manuscripts to high impact journals.

◆ Assisting with research proposals to be submitted to granting agencies.

四、申请方式

如申请此职位，请发邮件至邮箱info@zhengzicn.com，并附上以下内容。

◆ 当前简历

◆ 求职信

To apply for this position, please email with the following items attached.

◆Current CV

◆Cover letter